Biotin and derivatives
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | 98.0% | 884.92 g/mol | C38H64N2O21 | 25 MG
Bis-PEG13-NHS ester is a PEG-based N-hydroxysuccinimide (NHS) ester linker for research use in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs).
- Provides a bifunctional PEG13 spacer for conjugation to amines.
- Reactive NHS ester termini enable efficient coupling.
- High purity suitable for research applications.
- Molecular weight approximately 884.92 g/mol; molecular formula C38H64N2O21.
- Available in small pack sizes for research-scale synthesis.
Medchemexpress LLC Biotin-sar-oh | 154024-76-7 | 315.39 | C13H21N3O4S | 1 G
Biotin-sar-oh is a cleavable antibody-drug conjugate (ADC) linker bearing a biotin functionality, used in the synthesis of antibody-drug conjugates and probe development.
- Cleavable ADC linker for conjugation and release strategies.
- Biotinylated for affinity capture and detection.
- Molecular formula: C13H21N3O4S; molecular weight: 315.39.
- Available pack sizes: 250 mg and 1 g.
- CAS number: 154024-76-7.
Medchemexpress LLC Biotin-PEG3-iodoacetamide | 2306161-26-0 | 97.0% | 10 MG
Biotin-PEG3-iodoacetamide is a PEG-based linker combining a biotin tag, a three-unit PEG spacer, and an iodoacetamide reactive group. It selectively alkylates cysteine residues under mild conditions to introduce a biotin handle for affinity capture, detection, and enrichment workflows.
- Selective cysteine labeling via iodoacetamide chemistry.
- Biotin tag enables high-affinity streptavidin capture.
- PEG3 spacer improves solubility and reduces steric hindrance.
- Suitable for protein labeling, pull-downs, and detection assays.
- Provided as a small-molecule reagent for research use.
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | MFCD21363287 | 98.0% | 884.92 | C38H64N2O21 | 50 MG
Bis-PEG13-NHS ester is a bifunctional PEG-based linker containing N-hydroxysuccinimide (NHS) ester reactive groups that enable efficient amine conjugation; it is used as a cleavable linker in antibody-drug conjugate and PROTAC synthesis and for general bioconjugation chemistry.
- contains N-hydroxysuccinimide (NHS) ester reactive groups.
- functions as a cleavable linker for ADC and PROTAC synthesis.
- molecular formula C38H64N2O21, molecular weight 884.92.
- cas number 2221949-00-2 for unambiguous identification.
- purity 98.0% suitable for research applications.
- available in a 50 MG pack suitable for lab-scale synthesis.
- intended for research use only; not for human or clinical use.
Medchemexpress LLC Biotin-PFP ester | 120550-35-8 | 97.0% | 250 MG
Biotin-PFP ester is a pentafluorophenyl-activated biotin reagent for bioconjugation and linker chemistry. The activated ester reacts efficiently with primary amines to form stable amide bonds, enabling biotin tagging for affinity capture, detection, and proteomics workflows. Supplied as a research-grade solid suitable for small-scale synthesis.
- Activated pentafluorophenyl ester for efficient amide coupling
- Provides a biotin tag for affinity purification and detection
- Compatible with conjugation to primary amines under mild conditions
- High purity for reproducible synthetic and proteomics results
- Packaged for research-scale use and storage
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | MFCD23381190 | >97.0% | 501.49 | C20H31N5O10 | 500 MG
DOTA-NHS-ester is a bifunctional chelator containing a DOTA macrocycle and an N-hydroxysuccinimide (NHS) ester. It enables covalent conjugation to amine-containing biomolecules and subsequent radiometal chelation for imaging or radiotherapy research applications.
- Bifunctional chelator with NHS-ester for amine conjugation.
- High purity (≥97.0%) solid suitable for research.
- Molecular weight 501.49 and formula C20H31N5O10.
- Soluble in DMSO (50 mg/mL) and compatible with common in vivo formulations.
- Store powder at -20°C; solutions at -80°C (6 months) or -20°C (1 month).
- Available in a 500 mg pack size.
Medchemexpress LLC IL-12 Human Biotin 20ug | 20ug
IL-35 protein plays a key role in immune regulation forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production IL-12 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein expressed by HEK293 with C-Avi C-His labeled tag IL-12 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 40-45 kDa